| ncRNA name | hsa-miR-191 |
| ncRNA Category | miRNA |
| Disease name | retinoblastoma (RB) |
| Species | Homo sapiens |
| Tissues/Cell_line | RB samples, fetal retinas; human RB cell line Y79, Weri1 RB355 and NB1691, human bone osteosarcoma epithelial cell line U2OS |
| Methods | Sanger sequencing, qRT-PCR, immunoblot, Transcriptome sequencing, microarray |
| Expression pattern | down-regulated |
| Functional description | A microRNA predicted to target MDM4 (miR191) was downregulated in retinoblastoma relative to human fetal retinae and a subset of samples had somatic mutations that eliminated the miR-191 binding site in the MDM4 mRNA. |
| PubMed ID | 22916154 |
| Year | 2012 |
| Title | Analysis of MDM2 and MDM4 single nucleotide polymorphisms, mRNA splicing and protein expression in retinoblastoma. |
| Drug-related ncRNA | NO |
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